AMP: New CMR 1B Classification – Impacts on Cosmetics, Pet Care, and Detergents.

In December 2025, the European Committee for Risk Assessment (RAC) assigned a Category 1B CMR classification to Amino Methyl Propanol (AMP – CAS 124-68-5) as a substance potentially harmful to the developing fetus.

This decision will have significant consequences for the cosmetics, pet care, and detergent sectors, impacting formulations, labeling, safety, and product portfolio management.

What does the CMR 1B classification mean?

A CMR 1B substance is considered a high risk to reproductive health.

In the European regulatory framework, this means:

• severe limitations on use in consumer products,

• increased safety obligations,

• possible exclusion from market.

In cosmetic products, CMR 1B substances are prohibited. In other sectors, they are subject to increased controls..

Expected timeline for the ban in cosmetics

AMP is expected to be listed as a prohibited substance under the CLP Regulation.

The most likely scenario is::

Ban enforcement: September 2028

From this date, it will no longer be possible to:

• launch new products containing AMP onto the market,

• continue the sale of existing stocks.

A possible postponement to 2029 is under discussion, but it is advisable to plan for 2028.

Where AMP is used

AMP is used as a pH regulator and stabilizer.

In cosmetics:

• creams and serums

• sunscreens

• makeup

• hair products

• toners and lotions

In pet care and detergents:

• Pet shampoo

• Multipurpose cleaners

• Degreasers

• Professional cleaners

• Surface products

It is therefore a widely used ingredient.

Impact on the cosmetics industry

For cosmetics, the new classification entails:

• Gradual phaseout of AMP,

• Product reformulation,

• Recall of non-compliant formulations,

• Updating of technical dossiers.

Companies will need to plan ahead for the transition to alternative ingredients.

Impact on pet care and detergents

In the detergent and pet care sectors, AMP is not automatically banned, but it has significant effects..

Classification of mixtures

• Possible reclassification as "hazardous",

• New pictograms,

• Health warnings.

Labeling

• Graphic revision,

• New mandatory wording,

• Packaging update.

Worker safety

• Updated risk assessments,

• Exposure limitation,

• Specific training,

• Care for pregnant workers.

Commercial Impact

More and more customers and distributors are demanding products deemed "safe" by the consumer community.

What companies should do now

At this stage, it is advisable to:

✔ Map products containing AMPs

✔ Assess the impact on CLP classification

✔ Initiate alternative reformulations

✔ Plan inventory management

✔ Update SDSs and documentation

✔ Verify internal safety

An early approach allows for a more effective transition.

Conclusions

The AMP CMR 1B classification represents a structural change for the industry.

• In cosmetics, it will lead to a ban.

• In pet care and detergents, it will make use increasingly critical.

• In internal management, it will increase safety requirements.

Preparing early is essential to ensure operational continuity and competitiveness.

Regulatory Support

We support companies with:

• critical ingredient analysis,

• substitution strategies,

• reformulations,

• CLP classification,

• SDS updates,

• compliance assessments.

For a personalized evaluation of your product portfolio, contact us.